Pic EI 57-2: Start up sides and make sure to write down the color of your changing morphs. Drop spiders early when you can. Continue up sides to clear bubbles and shatter crystals. Then you drop the bombs using rainbow bubbles to help if necessary. The chain, locks and ceiling will then appear. Black bubbles make the angle shots to locks difficult.
Aiming Shot: After placing 2 bubbles under black bubbles on right you will have a good angle to break lock on left.
Pic EI 57-2 Aiming Shot: Place two matching colored bubbles under right column of black bubbles. After the area is cleared around left lock you will be able to reach and unlock it. Continue to work up right side and hit matching colors in middle to decrease loss of floor spiders. It is very easy to run out of bubbles especially if you get stuck under chain. The extra two bubbles are no longer necessary under black bubbles in order to break lock on right.
Once the chain is broken you will see the shadow bubble in middle. Remove or contain if possible and drop your black bubbles as you make your way through to ceiling hopefully shattering crystals as you proceed. There is a chance you will use additional single shots to break through crystals to drop ceiling. You can pass without running out of bubbles but maybe not the first time. :)