You need to break the Infection soon after the game have rolled out the last level of the first section at the Eternal Isles. I have done some counting while playing level 10 and the infection drips down all too low at latest on bubble number 11 or 12. (It depends on the order that the infected bubbles are coming down.) You stop the infection by aiming at the hotspots shown in the upper pic. Click on the picture to get a bigger version that you can have in a separate window while you play. The marks 2 and 3 are there to show what you need to pop away using the aiming spots.
In the picture to the left you see a yellow line, that line is drawn to mark the absolute final allowed place for the infection to reach. If it reach under it, you will not be able to see enough to get to the ceiling.
Tips from Cynthia Ledgley: “For E1-Lvl 10 one shot I discovered was the shot where the two bubbles are in an L shape with an apparent insurmountable gap and a doom bubble just above the gap. It’s at the spot you must hit in order to avoid the infected bubbles from dropping too low. To avoid having to aim past the doom bubble you can hit the bubble just to it’s side, on the bottom, in the middle and it will also take out the other too bubbles across the gap (hmmm does this make any sense at all LOL). Learning what kinds of shots you can actually make in this game is very helpful.”
Starting Bubbles: 50
Recommended Potions: All except Yellow Spiders
Good to have Charms: The Charm of Precision, the Charm of Insurance
Points needed for 1, 2, 3 Star: 90 000, 120 000, 220 000
Doom Skull Bubbles
3 star charmed video by Renata Pojezna